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*The following content is generated by AI and is for reference only.
Overview
Fmoc-D-Arg(Pbf)-OH is a protected amino acid derivative used in solid-phase peptide synthesis (SPPS). It features an Fmoc group on the alpha-amino and a Pbf group on the guanidine side chain to ensure orthogonal protection. Its molecular formula is C24H37N7O6S, with CAS number 156980-54-8.
Application
- Pharmaceutical Manufacturing: Essential building block for synthesizing therapeutic peptides and biologics.
- Peptide Drug Development: Used in R&D to construct complex sequences requiring D-arginine residues.
- Biochemical Research: Applied in creating peptide libraries for high-throughput screening assays.
Precautions
Store at -20°C under inert atmosphere to prevent degradation. Handle in a fume hood as it may cause skin irritation. Strictly regulated for human clinical use only via validated GMP-grade manufacturing processes.