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Overview
Fmoc-L-Hse(Trt)-OH is a protected serine derivative used in solid-phase peptide synthesis. It features an Fmoc group for N-terminal protection and a Trityl (Trt) group on the side chain hydroxyl to prevent unwanted reactions during coupling.
- Molecular Formula: C28H29NO5S
- CAS No: 146907-94-6
Application
- Peptide Synthesis: Essential building block for constructing complex therapeutic peptides requiring serine residues.
- Pharmaceutical R&D: Used in fragment-based drug discovery and optimization of bioactive compounds.
- Research Chemicals: Serves as a standard reagent for academic studies on amino acid chemistry.
Precautions
Store under inert atmosphere at -20°C to maintain stability. Handle with appropriate PPE including gloves and goggles, as derivatives may cause skin or eye irritation. Ensure proper ventilation during weighing and transfer processes.