Category:
Active Pharmaceutical Ingredients
CAS NO:
1391068-26-0
Standard:
EP,
Folic acid EP Impurity E, chemically identified as N5,N10-methylenetetrahydrofolic acid (CAS 6948-27-0), is a critical degradation product and reference standard in pharmaceutical synthesis. It typically arises during the reduction of folic acid or via metabolic pathways involving methylene transfer.
Store strictly below -20°C in desiccated conditions to prevent hydrolysis. Handle with appropriate PPE; avoid inhalation of dust. Not intended for direct clinical administration but used solely for analytical characterization.