Category:
Intermediates&Fine Chemicals
CAS NO:
138071-82-6
Standard:
In-house Standards,
Gadobutrol is a non-ionic, high-relaxivity Gadolinium-based contrast agent (GBCA) used in magnetic resonance imaging. Its core synthesis involves chelating gadolinium with the macrocyclic ligand DO3A-buta to ensure exceptional thermodynamic stability. The chemical formula is C19H32GdN5O10 and CAS number is 114687-38-8.
Contraindicated in patients with severe renal impairment due to nephrogenic systemic fibrosis risk. Requires strict storage at controlled room temperature away from direct light. Administer only under professional medical supervision with emergency resuscitation equipment available.