Gadoteridol is a kind of contrast media for MRI.
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Overview
Gadoteridol is a non-ionic gadolinium-based contrast agent (GBCA) used for magnetic resonance imaging. It is synthesized via complexation of Gd³⁺ ions with the macrocyclic ligand HP-DO3A. The chemical formula is C₁₉H₂₈GdN₅O₁₀ and CAS number is 145706-72-9.
Application
- Diagnostics: Enhances visualization of brain, spine, and body tissues in MRI scans.
- Neurology: Detects blood-brain barrier disruptions in tumors, multiple sclerosis, or strokes.
- Oncology: Assists in tumor characterization and monitoring treatment response.
Precautions
Contraindicated in patients with severe renal impairment due to nephrogenic systemic fibrosis risk. Store at controlled room temperature away from light. Use only under strict medical supervision with appropriate dosing protocols.