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Overview
Gadoversetamide is a gadolinium-based contrast agent (GBCA) used for magnetic resonance imaging. It is synthesized via chelation of Gd³⁺ with the versetamide ligand to ensure stability and reduce toxicity. Molecular Formula: C₁₄H₂₀GdN₃O₈; CAS Number: 100974-28-5.
Application
- Diagnostics: Enhances visualization of vascular structures in neuroimaging and angiography.
- Oncology: Facilitates tumor detection and characterization through improved tissue contrast.
- Research: Supports pharmacokinetic studies and functional MRI protocols.
Precautions
Contraindicated in patients with severe renal impairment due to nephrogenic systemic fibrosis risk. Store in a cool, dry place away from direct sunlight. Strict adherence to dosage guidelines is mandatory to prevent gadolinium deposition.