Appearance White crystal conforms
Loss on Drying Not more than 0.50% 0.36%
Melting Point (°C) 140 to 146°C 142°C
Assay Not less than 98.5% 98.9%
PH 2.8-3 2.9
*The following content is generated by AI and is for reference only.
Overview
Glycine ethyl ester hydrochloride is a protected amino acid derivative widely used in peptide synthesis. Its core process involves the esterification of glycine followed by salt formation with hydrogen chloride. The compound features the molecular formula C4H10ClNO2 and carries CAS No. 5698-47-3.
Application
- Pharmaceutical Manufacturing: Serves as a key building block for synthesizing complex dipeptides and tripeptides.
- Biochemical Research: Utilized in solid-phase peptide synthesis (SPPS) to facilitate coupling reactions.
- Material Science: Applied in developing functional biomaterials and drug delivery systems.
Precautions
- Store under inert atmosphere at 2-8°C to prevent hydrolysis and degradation.
- Handle with appropriate PPE due to potential respiratory irritation and corrosive properties.
- Not intended for direct clinical administration without further derivatization.