Gonadorelin, also known as GnRH or LHRH, is produced by neuroendocrine cells within the hypothalamus. The hormone is secreted pulsatilely. Gonadorelin induces the release of LH and FSH from the anterior pituitary.
After a transient increase, continuous a
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Overview
Gonadorelin is a synthetic decapeptide identical to native gonadotropin-releasing hormone (GnRH). Produced via solid-phase peptide synthesis, its molecular formula is C49H67N15O12 with CAS number 27175-88-0.
Application
- Diagnostics: Evaluating pituitary-gonadal axis function in reproductive disorders.
- Fertility Research: Stimulating gonadotropin release for assisted reproduction studies.
- Endocrinology: Investigating hormonal regulation mechanisms in clinical trials.
Precautions
Strictly for research use only; not approved for human therapeutic administration. Store lyophilized powder at -20°C under inert atmosphere. Handle with PPE to prevent dermal exposure and inhalation of particulates.