Category:
Chiral Intermediates
Standard:
In-house Standards,
| Quality standard | Q/YH |
| Items | Standard |
| Appearance | Colorless transparent solution |
| Boiling point | 112.5°C |
| Density | 0.715 |
| Refractive index | -1.422 |
| Purity | ≥99% |
Hexamethyldisilazane (HMDS) is a volatile silylating agent produced via the reaction of dimethylamine with chlorotrimethylsilane. It serves as a critical reagent for converting hydroxyl groups into trimethylsilyl derivatives. Molecular formula: C6H19N Si2; CAS No.: 999-97-3.
Strictly store under inert atmosphere at low temperatures due to moisture sensitivity. Avoid contact with skin and eyes; use appropriate PPE including respirators. Do not ingest or inhale vapors, as it decomposes into toxic silanols and ammonia upon hydrolysis.