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Overview
Histrelin acetate is a synthetic decapeptide analog of GnRH, designed for sustained release. Its molecular formula is C64H92N18O14 with CAS No. 57773-63-0.
Application
- Pediatric Endocrinology: Treatment of central precocious puberty to delay premature sexual development.
- Oncology: Management of advanced prostate cancer by suppressing testosterone production.
- Fertility Research: Used in vitro to study gonadotropin secretion mechanisms.
Precautions
Strictly contraindicated in pregnancy and hypersensitivity cases. Requires storage at controlled room temperature (20°C–25°C) protected from light. Handling must follow standard pharmaceutical safety protocols to avoid inhalation or skin contact.