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Overview
Hydrocortisone sodium succinate is a water-soluble ester prodrug of hydrocortisone, synthesized via succinylation to enhance injectability. It serves as a critical corticosteroid API for rapid systemic delivery.
- Molecular Formula: C23H31NaO8
- CAS No: 2392-40-5
Application
- Emergency Medicine: Treatment of acute adrenal insufficiency and severe anaphylactic shock.
- Inflammation Management: Adjunct therapy for rheumatoid arthritis and severe allergic reactions.
- Oncology Support: Mitigation of chemotherapy-induced nausea and cerebral edema.
Precautions
- Storage: Maintain in dry conditions below 25°C, protected from light to prevent degradation.
- Safety: Requires strict medical supervision due to risks of hyperglycemia and immunosuppression.
- Contraindications: Avoid use in active untreated fungal infections or known hypersensitivity.