Category:
Chiral Intermediates
CAS NO:
180637-89-2
Standard:
USP,
-
Eletriptan hydrobromide is a selective 5-HT1B/1D receptor agonist used for acute migraine treatment. Key intermediates include (1R,2S,5S)-6,6-dimethyl-3-norbornylamine derivatives and specific indole precursors. The synthesis involves rigorous chiral resolution and bromination steps. Molecular formula: C20H28N2·HBr; CAS No.: 174799-50-1.
Strictly contraindicated for patients with uncontrolled hypertension or history of ischemic heart disease. Store intermediates in cool, dry conditions below 25°C under inert atmosphere to prevent degradation. Ensure PPE usage during handling due to potential respiratory sensitization.