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Overview
Ipilimumab is a recombinant human IgG1 kappa monoclonal antibody targeting CTLA-4. Produced via CHO cell fermentation, its molecular formula is C6702H10480N1792O2032S76 (CAS: 1446521-42-1).
Application
- Oncology Manufacturing: Bulk supply for metastatic melanoma and renal cell carcinoma therapies.
- Immunotherapy Development: Critical reagent for checkpoint inhibitor combination studies.
- Clinical Trials: Active pharmaceutical ingredient (API) for Phase III oncology investigations.
Precautions
Strictly store at 2°C to 8°C. Administer only under specialist supervision due to risk of immune-mediated adverse reactions. Avoid freeze-thaw cycles during logistics handling.