Irinotecan is a drug used for the treatment of cancer. Its main use is in colon cancer, in particular, in combination with other chemotherapy agents. This includes the regimen FOLFIRI, which consists of infusional 5-fluorouracil, leucovorin, and irinotecan.
Irinotecan HCl gets Chinese local GMP certificate and has been approved by US-FDA and Japanese PMDA.
Irinotecan HCl Injection gets Chinese local GMP certificate and MA issude from US-FDA and Japanese PMDA.
Irinotecan HCl is a semisynthetic camptothecin derivative and topoisomerase I inhibitor. Synthesized via chemical modification of natural compounds, it serves as a critical anticancer prodrug. Molecular Formula: C33H38N4O6; CAS No.: 119413-74-2.
Requires strict adherence to GMP standards during handling. Store at controlled room temperature away from moisture. Clinically limited by severe neutropenia risks; requires dose adjustment based on UGT1A1 genotype testing.