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Overview
ISAVUCONAZOLE HYDROCHLORIDE is a broad-spectrum triazole antifungal agent used for invasive aspergillosis. The core synthesis involves chiral catalysis and salt formation to ensure high purity. Molecular Formula: C20H19ClN6O, CAS No.: 458788-83-9.
Application
- Fungal infection treatment in immunocompromised patients.
- Invasive pulmonary aspergillosis therapy where voriconazole fails.
- Manufacturing of sterile injectable formulations for hospital supply chains.
Precautions
Contraindicated with strong CYP3A4 inducers. Requires strict temperature control (2-8°C) during storage to maintain stability. Medical personnel must handle powder forms with appropriate respiratory protection to avoid inhalation risks.