*The following content is generated by AI and is for reference only.
Overview
Isavuconazonium Sulfate is the water-soluble prodrug of isavuconazole, a broad-spectrum triazole antifungal. Synthesized via salt formation to enhance bioavailability, its molecular formula is C37H41N5O4S·H2SO4 with CAS No. 186920-79-0.
Application
- Invasive Aspergillosis and Mucormycosis treatment in immunocompromised patients.
- Alternative therapy for patients intolerant to amphotericin B or voriconazole.
- Severe fungal infections requiring intravenous or oral administration flexibility.
Precautions
Contraindicated with strong CYP3A4 inducers like rifampin. Monitor QT interval prolongation risks during therapy. Store in controlled conditions below 25°C in dry environments away from direct light.