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Overview
Isotretinoin (CAS 13103-17-6) is a terpenoid retinoid synthesized via chemical oxidation and rearrangement. Its molecular formula is C20H28O2, serving as the primary active ingredient in dermatological formulations.
Application
- Dermatology: Treatment of severe recalcitrant nodular acne.
- Pharmaceuticals: Manufacturing of oral capsules and topical gels.
- Research: Development of new anti-proliferative agents.
Precautions
Strictly contraindicated in pregnancy due to high teratogenicity. Requires storage in cool, dry conditions away from light. Handling demands PPE to prevent skin contact and inhalation exposure.