Category:
Other Specialized Reagents
CAS NO:
1609-47-8
Standard:
ChP,
Diethyl pyrocarbonate (DEPC) is a potent carbodiimide reagent used primarily for nucleic acid decontamination. Its molecular formula is C5H10O3 with CAS No. 646-39-7. The compound functions by ethylating nucleophilic groups, effectively inactivating RNases.
Strictly avoid contact with skin and eyes; use in well-ventilated fume hoods. Store in a cool, dry place away from moisture to prevent hydrolysis into ethanol and CO2. Not approved for direct clinical administration due to toxicity.