【产品名称】:帕米膦酸二钠水合物
【Product Name】:Pamidronate disodium salt hydrate, 98%, farnesyl diphosphate synthase inhibitor
【产品规格】:法尼基焦磷酸合成酶抑制剂
【CAS】:57248-88-1
【MP】:300℃
【Storage】:Freezer -20℃
*The following content is generated by AI and is for reference only.
Overview
Pamidronate disodium salt hydrate (CAS 10421-65-7) is a nitrogen-containing bisphosphonate acting as a potent farnesyl diphosphate synthase inhibitor. Synthesized via phosphite condensation, its molecular formula is C3H14Na2O7P2.
Application
- Oncology Research: Inhibits osteoclast-mediated bone resorption in metastatic studies.
- Biochemical Assays: Used to validate protein geranylgeranylation pathways.
- Dermatology: Investigated for treating hyperproliferative skin disorders.
Precautions
- Requires strict storage below 25°C in dry conditions to prevent hydration changes.
- Handling requires PPE due to potential respiratory and dermal irritation.
- Not approved for direct clinical use without pharmaceutical-grade formulation.