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Overview
L-Glutamic acid 5-benzyl ester is a protected amino acid derivative synthesized via esterification of L-glutamic acid with benzyl alcohol. It serves as a critical intermediate in peptide synthesis and pharmaceutical manufacturing. Molecular Formula: C12H15NO4; CAS No.: 6087-27-8.
Application
- Pharmaceutical Synthesis: Acts as a building block for constructing complex peptidomimetics and antibiotic precursors.
- Research & Development: Utilized in solid-phase peptide synthesis (SPPS) to protect carboxyl groups during chain elongation.
- Material Science: Employed in the development of bio-compatible polymers and functionalized hydrogels.
Precautions
- Safety: Avoid inhalation of dust; wear appropriate PPE including gloves and eye protection.
- Storage: Store in a cool, dry place under inert atmosphere to prevent hydrolysis or degradation.
- Regulatory: Not approved for direct human consumption; restricted to industrial and laboratory use only.