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Overview
Lacosamide is a synthetic anticonvulsant drug, chemically defined as (2R)-2-acetamido-N-benzyl-3-methoxypropionamide. Its core synthesis involves asymmetric hydrogenation and amide coupling. Molecular formula: C13H20N2O3; CAS No.: 175486-90-7.
Application
- Epilepsy management for partial-onset seizures in adults and pediatric patients.
- Adjunctive therapy for primary generalized tonic-clonic seizures.
- Neuropathic pain modulation in specific clinical off-label protocols.
Precautions
Contraindicated in patients with known hypersensitivity to lacosamide or its excipients. Strict adherence to cardiac conduction monitoring is required due to potential PR interval prolongation. Store in a cool, dry place below 25°C away from direct sunlight.