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Overview
Lapatinib is a small-molecule tyrosine kinase inhibitor targeting EGFR and HER2. Molecular Formula: C29H26ClFN4O3; CAS No.: 231277-92-2. Core synthesis involves heterocyclic coupling and halogenation under strict GMP conditions.
Application
- Pharmaceutical manufacturing for metastatic breast cancer therapy.
- Combination treatment with capecitabine in HER2-positive cases.
- Research reagent for oncology drug discovery and mechanism studies.
Precautions
Requires prescription only; monitor hepatic function and cardiac toxicity. Store at controlled room temperature (20-25°C) in moisture-proof, light-resistant containers away from incompatible oxidizers.