Category:
Cardiovascular System Drugs
CAS NO:
936623-90-4
Standard:
In-house Standards,
LCZ696
CAS:936623-90-4
MF: C51H69N6Na3O10.5
MW: 1002.47
LCZ696, branded as Entresto, is a novel fixed-dose combination of sacubitril and valsartan. It functions as an angiotensin receptor-neprilysin inhibitor (ARNI) designed to treat heart failure with reduced ejection fraction.
Contraindicated in patients with history of angioedema or concurrent ACE inhibitor use. Requires strict storage at controlled room temperature away from moisture.