Category:
Active Pharmaceutical Ingredients
CAS NO:
936623-90-4
Standard:
In-house Standards,
LCZ696, known as sacubitril/valsartan, is a fixed-dose combination of a neprilysin inhibitor and an angiotensin II receptor blocker. Its molecular formula is C42H58N10O7 (CAS: 132913-65-2). The core process involves co-crystallization to enhance stability and bioavailability.
Avoid use in pregnancy due to fetal toxicity. Monitor renal function and potassium levels strictly. Store in sealed containers at controlled room temperature away from moisture.