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Overview
Ledipasvir is a potent HCV NS5A inhibitor used in antiviral therapy. Its molecular formula is C27H19F4N3O6 with CAS number 1253928-00-3. Industrial synthesis involves complex multi-step organic reactions.
Application
- Pharmaceutical Manufacturing: Primary API for treating Hepatitis C virus (HCV) genotype 1 infections.
- Combination Therapy: Key component in fixed-dose combinations with sofosbuvir.
Precautions
Requires strict storage at controlled room temperature away from moisture. Clinical use is limited to specific HCV genotypes and requires monitoring for potential drug-drug interactions.