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Overview
Ledipasvir Acetone refers to a specialized solvent system or intermediate formulation involving the antiviral drug Ledipasvir dissolved in acetone, primarily utilized during pharmaceutical manufacturing processes. The core molecular structure of Ledipasvir is C28H20F3N5O6 (CAS: 1279247-05-8). This process ensures high purity and solubility for subsequent crystallization steps.
Application
- Hepatitis C Treatment: Key ingredient in direct-acting antiviral (DAA) combination therapies targeting NS5A protein.
- Solvent Extraction: Used as a processing aid in the purification of active pharmaceutical ingredients (APIs).
- Formulation Development: Facilitates the creation of stable solid dispersions for oral dosage forms.
Precautions
Strictly handle under inert atmosphere due to flammability of acetone. Store in cool, dry, well-ventilated areas away from ignition sources. Personal protective equipment (PPE) including respirators and chemical-resistant gloves is mandatory to prevent inhalation hazards and skin contact.