Category:
Intermediates&Fine Chemicals
CAS NO:
1374639-75-4
Standard:
In-house Standards,
Lee011 succinate is the sodium succinate salt of abemaciclib, a potent CDK4/6 inhibitor. Manufactured via pharmaceutical synthesis and crystallization, its molecular formula is C28H35N7O2·C4H4NaO4 (CAS: 2094296-66-7).
Strictly contraindicated in severe hepatic impairment. Requires storage at controlled room temperature (20°C to 25°C) in dry conditions. Handling mandates PPE to prevent inhalation or dermal exposure during processing.