Category:
Active Pharmaceutical Ingredients
CAS NO:
NA
Standard:
In-house Standards,
Linaclotide is a synthetic guanylate cyclase-C agonist used for chronic constipation and IBS-C. Its core process involves solid-phase peptide synthesis targeting the C-terminal 14-amino acid sequence. Formula: C56H89N17O20S2; CAS: 109227-43-8.
Contraindicated in pediatric patients under 6 years due to risk of severe dehydration. Store API at controlled room temperature (20°C–25°C) in moisture-proof containers to prevent hydrolysis. Strict regulatory compliance required for clinical distribution.