Category:
Intermediates&Fine Chemicals
CAS NO:
851199-59-2
Standard:
In-house Standards,
Linaclotide is a synthetic cyclic peptide agonist of the guanylate cyclase-C receptor. It is manufactured via solid-phase peptide synthesis to treat chronic idiopathic constipation and IBS-C. Its molecular formula is C46H68N12O17S2, with CAS No. 593451-46-0.
Contraindicated in pediatric patients under six years due to risk of severe dehydration. Store lyophilized powder at -20°C protected from light and moisture. Avoid inhalation during manufacturing; use appropriate PPE including respirators.