Category:
Intermediates&Fine Chemicals
CAS NO:
84392-17-6
Standard:
In-house Standards,
Lomitapide Mesylate (CAS 84392-17-6) is a potent inhibitor of microsomal triglyceride transfer protein (MTP), designed for treating homozygous familial hypercholesterolemia. Its molecular formula is C25H30F3N5O6S. The core manufacturing process involves precise asymmetric synthesis and salt formation to ensure high chemical purity suitable for pharmaceutical grade standards.
Strictly contraindicated in pregnancy due to teratogenic risks. Storage requires cool, dry conditions below 25°C protected from light. Clinical use mandates regular liver function monitoring and dietary fat restrictions to mitigate hepatotoxicity risks.