Category:
Cardiovascular System Drugs
CAS NO:
/
Standard:
In-house Standards,
/
Losartan potassium is a widely used angiotensin II receptor blocker (ARB). It serves as the active pharmaceutical ingredient in hypertension management. The standard synthesis involves condensation of biphenyl derivatives with tetrazole, followed by salt formation with potassium hydroxide. Key specifications include molecular formula C22H22KN6O and CAS number 159187-04-5.
Contraindicated in pregnancy due to fetal toxicity risks. Store in sealed containers at controlled room temperature below 25°C to prevent degradation. Personnel must wear appropriate PPE during handling to avoid inhalation or skin contact.