All sizes of lyophilization use rubber stopper
*The following content is generated by AI and is for reference only.
Overview
Lyophilization rubber stoppers are precision-engineered seals designed for freeze-drying processes. Manufactured from chlorobutyl or bromobutyl elastomers, they feature low extractables and high gas permeability to ensure efficient sublimation while maintaining sterility.
Application
- Pharmaceutical Industry: Used in aseptic filling lines for vaccines, antibiotics, and biologics.
- Bio-Research: Compatible with lyophilizers for sample preservation in laboratory settings.
- Equipment: Specifically matched with rotary vial freezers and tray dryers.
Precautions
- Temperature: Operate strictly within -80°C to +250°C limits during sterilization cycles.
- Pressure: Maintain vacuum integrity below 1 mbar during primary drying phases.
- Maintenance: Inspect for compression set or surface cracking after every 50 cycles.