Category:
Other Specialized Reagents
CAS NO:
1224601-12-0
Standard:
In-house Standards,
Lys(MMT)-PAB-oxydiacetamide-PEG8-N3 is a specialized heterobifunctional linker for Antibody-Drug Conjugates (ADCs). It features an acid-labile PAB spacer, a PEG8 chain for solubility, and an azide handle for strain-promoted click chemistry. The molecule integrates an MMT-protected lysine moiety to ensure orthogonal stability during synthesis.
Store strictly under inert atmosphere at -20°C to prevent hydrolysis and oxidation. Handle with appropriate PPE due to potential sensitization; avoid exposure to strong acids which may cleave the PAB linker prematurely. Not intended for direct clinical administration without further formulation.