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Malic Acid

Malic Acid

Category:
Natural Extracts
Standard:
In-house Standards,
Price Range:
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Main Sales Markets:
North America,Central/South America,Eastern Europe,Australasia,Middle East,Africa
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Basic Info

Pharmacopoeia
In-house Standards
Grade
Food Grade
Is Manufacturer
YES

Product Description

About The Detailed Introduction Of Malic Acid Powder?

 

Bulk Malic acid, also known as 2-hydroxysuccinic acid, has two stereoisomers due to an asymmetric carbon atom in the molecule. In nature, it exists in three forms, namely D-malic acid, L-malic acid and its mixture DL-malic acid. It is a white crystal or crystalline powder. It is highly hygroscopic and easily soluble in water and ethanol. It has a special pleasant sour taste. Malic acid is mainly used in the food and pharmaceutical industries.
There are three types of malic acid: L-malic acid, D-malic acid, and DL-malic acid. L-malic acid is a product of the human body's tricarboxylic acid cycle, so the human body can only metabolize L-malic acid. L-malic acid naturally occurs in fruits such as apples, grapes, and lemons. If extracted from fruits, the content is low and the cost is high, making it impossible to mass-produce industrially. What can only be produced by the catalytic synthesis of fumaric acid (fumaric acid) is DL-malic acid. Since the human body cannot metabolize DL-malic acid, although European and American countries allow DL-malic acid to be used as a food additive, people always have Feelings of insecurity. Malic acid produced by microbial methods is all L-malic acid. Therefore, all malic acid used today is produced by microorganisms. Malic acid used in food, medicine, etc. basically replaces DL-malic acid with L-malic acid. acid.

 

Product Details List

 

  D-malic acid L-malic acid DL-malic acid
Molecular formula C4H6O5
Molecular weight 134.09
CAS 636-61-3 97-67-6 617-48-1
Density 1.595g/cm3 1.595g/cm3 1.601
Melting point 98-104℃ 101-103℃ 130-132℃
Boiling point 306.4℃ 306.4℃ 206.4℃
Flash point 153.4℃ 153.4℃ 153.4℃
Refractive index 1.529 1.529 1.529
Specific rotation +2.92° (methanol) -2.3° (8.5g/100ml water)  
Solubility soluble in water, methanol, ethanol, acetone. Easily soluble in water, methanol, acetone, dioxane, insoluble in benzene soluble in water, methanol, ethanol, dioxane, acetone, insoluble in benzene

The most common is the levorotatory form, L-malic acid, found in the juice of immature hawthorn, apple and grape fruits. It can also be obtained from fumaric acid through biological fermentation. It is an important intermediate product of the human body's internal circulation and is easily absorbed by the body. Therefore, it is widely used in food, cosmetics, medical and health products and other fields as a food additive and functional food with excellent performance. The racemate can be prepared from fumaric acid or maleic acid under the action of a catalyst under high temperature, high pressure and water vapor.
 

What Are The Benefits?

 

1. Universal Energy Booster

As mentioned earlier, malic acid is produced by the body and is a key player in the Krebs cycle. This cycle involves the metabolism of carbohydrates, proteins, and fatty acids to produce adenosine triphosphate, often shortened to ATP.
This intricate complex of organic chemicals provides cellular energy to all living organisms on Earth.

2. Helps Treat Fibromyalgia And Chronic Fatigue Syndrome

The combination of magnesium and malate is considered an alternative treatment for fibromyalgia, but more research is needed. Some studies report significant improvements in fibromyalgia symptoms after magnesium malate supplementation.

Magnesium malate is also sometimes used for chronic fatigue syndrome.

What is malic acid? It is a form of malic acid.

The main symptom of chronic fatigue syndrome, or CFS, is extreme fatigue. Fibromyalgia is another condition in which fatigue is the main symptom.

Since malate plays an integral role in the energy-producing Krebs cycle that occurs in the body, it makes sense that some people choose to supplement with malate in these situations. However, there is not a lot of research to date supporting the use of malate supplements in these conditions.

3. Promote Better Athletic Performance

As a supplement, Bulk Malic acid is used to enhance athletic performance and prevent post-exercise muscle fatigue. It is sometimes taken with creatine, a very popular supplement for people who want to increase lean muscle mass.

A 2015 study published in Acta Physiologica Hungarica examined the effects of creatine malate supplementation on distance runners and sprinters. After six weeks of supplementation and strength training, the researchers observed a significant increase in growth hormone in the sprinter group, with improvements in physical performance in both sprinters and distance runners.

For distance runners, the distance they run increases significantly.

4. Solve Common Skin Problems (Such As Wrinkles And Acne)

It's not uncommon for this acid to be used in skin care products. Due to its antioxidant and exfoliating properties, it is commonly used to address a range of skin concerns, including fine lines and wrinkles, hyperpigmentation, acne, enlarged pores, milia, warts, calluses, and more.

Sometimes it is naturally derived, but it can also be synthetic or artificial. It is often combined with glycolic acid and lactic acid.

Malic acid is a very effective skin refiner because it promotes the shedding of the outer layer of skin cells. The shedding it promotes can have anti-aging effects, as cell turnover slows as we age.

It also helps remove pore-clogging debris that can cause acne.

5. Improve Oral Health

Some studies show that this acid can improve symptoms of xerostomia (the fancy name for dry mouth) by stimulating saliva production in the mouth. Healthy saliva production also helps prevent oral bacterial overgrowth.

6. Promote Iron Absorption

Everyone needs to get iron from their diet. Getting enough of this nutrient is especially important for pregnant women and people with anemia.

One study suggests that vegetables rich in vitamin C and malic acid, such as tomatoes and potatoes, are excellent choices if you want to improve iron absorption.

 

Production Method


The production method of L-malic acid has developed from the early single extraction method to the following methods: extraction method, chemical synthesis method, one-step fermentation method, two-step fermentation method, immobilized enzyme or cell transformation method. At present, the existing problem is still the lack of excellent production strains. While researching and breeding excellent strains, it is very necessary to focus on strengthening the research on extraction technology and other related technologies. It is very necessary to do a good job in the research and development of upstream and downstream engineering supporting technologies.

 

Preparation


(1) Extraction method: Boil the juice of immature apples, grapes, peaches, etc., add lime water to generate calcium salt precipitation, and then process it to generate free malic acid.
(2) Synthesis method: catalytically oxidize benzene to obtain maleic acid and fumaric acid, which are then hydrated under high temperature and pressure. The conditions for the hydration reaction are usually 3-5 hours at 180-220°C and 1.4-1.8MPa pressure. The reaction product is mainly malic acid and a small amount of fumaric acid. Adjust the content of malic acid to 40% at 40°C and cool the solution to about 15°C. Filter and separate fumaric acid crystals. The mother liquor is concentrated and centrifuged. solid to obtain crude malic acid, which is then refined and crystallized to obtain the finished product.
(3) Fermentation method: Use biological enzyme fermentation to produce L-malic acid from fumaric acid.

 

What Are The Application Directions?

 

Food Industry Applications
Bulk Malic acid is an important component of natural juice. Compared with citric acid, it has greater acidity (the sourness is 20% stronger than citric acid), but has a soft taste (has a high buffering index), has a special flavor, and does not damage the mouth and teeth. It is metabolically beneficial to the absorption of amino acids and does not accumulate fat. It is a new generation of food sourness. It is hailed as "the most ideal food sourness" by the biological and nutritional circles. It has been replacing citric acid in foods for the elderly and children since 2013.
It is an organic acid necessary for the human body and an ideal low-calorie food additive. When 50% L-malic acid and 20% citric acid are combined, a strong natural fruit flavor can be presented.
L-malic acid is a circulating intermediate of tricarboxylic acid in living organisms. It tastes close to natural fruit juice and has a natural flavor. Compared with citric acid, it produces lower calories and has a better taste. Therefore, it is widely used in wine, beverages, and jams. , chewing gum and other foods, and has the tendency to gradually replace citric acid. It is one of the organic acids with the largest consumption and good development prospects in the world's food industry.
Containing natural emollient ingredients, it can easily dissolve the "sticky matter" stuck between dry scaly dead cells, thereby removing wrinkles on the skin surface and making the skin white, smooth and elastic. It is very popular in cosmetic formulations; L-malic acid can be used to prepare a variety of flavors and spices, and is used in a variety of daily chemical products, such as toothpaste, shampoo, etc.; compared with citric acid, L-malic acid has a softer sour taste It is unique, so it is used abroad to replace citric acid as a new detergent additive and used to synthesize high-end special detergents.

Malic acid

Pharmaceutical Industry Applications
Malic acid can be added to various tablets and syrups to present a fruity flavor and facilitate absorption and diffusion in the body. It is often added to complex amino acid injections to improve the utilization of amino acids. Its sodium salt is an effective drug in the treatment of liver dysfunction, especially hypertension. L-potassium malate is a good potassium supplement that can maintain the body's water balance and treat edema, hypertension, and fat accumulation.
L-malic acid can be used in pharmaceutical preparations, tablets, syrups, and can also be mixed into amino acid solutions, which can significantly improve the absorption rate of amino acids; L-malic acid can be used to treat liver disease, anemia, low immunity, uremia, and hypertension. It can treat various diseases such as blood pressure and liver failure, and can reduce the toxic effects of anti-cancer drugs on normal cells. It is also used in the preparation and synthesis of anthelmintic agents, anti-tartar agents, etc. In addition, L-malic acid can also be used as an industrial cleaning agent, resin curing agent, synthetic material plasticizer, feed additive, etc.
Daily Chemical Industry Application
L-Zinc malate is used in toothpaste as an anti-plaque agent and anti-calculus agent, in synthetic flavoring formulations, etc.
Chemical Industry Applications
It can be used as one of the synthetic raw materials for descaling agents and fluorescent whitening agents. Added to shellac varnish or other varnishes, it can prevent the paint surface from crusting. The polyester resin and alkyd resin produced with this acid are plastics with special uses.

 

Company Introduction And Certificates Obtained

Shaanxi Yuantai Biological Technology Co., Ltd (YTBIO) was established in 2014, mainly supplying Bulk Malic acid etc. We have our own factories, R&D and quality inspection teams, and have the conditions for development, production, and quality assurance. At present, we have obtained ISO9001, ISO22000, HALAL, KOSHER, HACCP, FDA, and other certificates. Therefore, the quality of our products is guaranteed, and it is our original intention to bring high-quality products to customers.

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