Category:
Intermediates&Fine Chemicals
CAS NO:
66547-09-9
Standard:
In-house Standards,
Maytansinoid AP-3 is a potent microtubule-disrupting agent derived from maytansine, primarily utilized as a cytotoxic payload in Antibody-Drug Conjugates (ADCs). Its synthesis involves complex semi-synthetic pathways to ensure high purity and stability. The compound features the molecular formula C41H56N2O10 with CAS number 129877-87-4.
Strictly limited to research use only; not approved for clinical administration in raw form. Requires storage at -20°C under inert atmosphere to prevent hydrolysis. Personnel must utilize appropriate PPE due to high cytotoxicity and potential reproductive hazards.