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Overview
Methyl ceftamime is a cephalosporin derivative used as an intermediate in pharmaceutical synthesis. Its core process involves esterification of ceftamime to enhance lipophilicity for improved bioavailability. The molecular formula is C20H21N7O6S2 with CAS No. 89646-55-3.
Application
- Antibiotic Manufacturing: Precursor for semi-synthetic beta-lactam antibiotics targeting Gram-negative bacteria.
- Pharmaceutical R&D: Used in stability studies and formulation development for broad-spectrum antimicrobial agents.
- Quality Control: Reference standard for HPLC analysis in active pharmaceutical ingredient verification.
Precautions
- Storage: Keep in a cool, dry place below 25°C protected from light to prevent hydrolysis.
- Safety: Handle with appropriate PPE; avoid inhalation or skin contact due to potential sensitization.
- Regulatory: Not for direct clinical use; strictly regulated under GMP guidelines for intermediate handling.