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Overview
Metreleptin is a recombinant human leptin produced via recombinant DNA technology. It mimics endogenous leptin to regulate energy balance. Molecular formula: C179H284N50O54S; CAS No.: 67888-96-4.
Application
- Metabolic Disorders: Treatment of generalized lipodystrophy and HIV-associated lipodystrophy.
- Clinical Trials: Investigational use in metabolic syndrome and obesity management.
- Research: Study of adipokine signaling pathways in pharmaceutical R&D.
Precautions
Contraindicated in patients with active malignancy or history of hypersensitivity. Requires strict cold chain storage at 2°C to 8°C. Administered subcutaneously under medical supervision to prevent injection site reactions and hypoglycemia.