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Overview
Mycophenolate mofetil is a potent immunosuppressive prodrug widely utilized in pharmaceutical manufacturing. Synthesized via esterification, its core structure features the molecular formula C₂₃H₂₉NO₇ and CAS No. 128794-94-5.
Application
- Organ Transplantation: Prevention of acute rejection in kidney, heart, and liver transplant recipients.
- Rheumatology: Treatment of autoimmune disorders like lupus nephritis.
- Dermatology: Management of severe cutaneous conditions such as pemphigus vulgaris.
Precautions
Strictly contraindicated during pregnancy due to teratogenic risks. Requires storage in cool, dry environments below 25°C. Personnel must utilize PPE to prevent inhalation or dermal exposure during handling.