Category:
Chiral Intermediates
CAS NO:
152460-09-8
Standard:
In-house Standards,
Antitumor drugs
N-(2-methyl-5-nitrophenyl)-4-(3-pyridyl)-2-pyrimidineamine (nitro-imatinib) is a key synthetic intermediate for the production of imatinib mesylate. Its molecular formula is C17H16N6O2 and CAS number is 209282-38-4. The core process involves selective nitration of the phenyl precursor followed by coupling with pyridine derivatives.
Store under inert atmosphere at temperatures below 25°C to prevent degradation. Personnel must utilize appropriate PPE due to potential mutagenic properties associated with nitro-aromatic compounds during handling.