Category:
Pharmaceutical Excipients
CAS NO:
333753-67-6
Standard:
USP,
N-[(2R)-3-[[3-Fluoro-4-(4-morpholinyl)phenyl]amino]-2-hydroxypropyl]acetamide is the chemical name for Afatinib, a potent, irreversible ErbB family blocker. Its molecular formula is C21H26FN3O4 with CAS No. 850140-73-3. Manufactured via multi-step organic synthesis involving heterocyclic coupling and chiral resolution.
Strictly contraindicated in pregnancy due to teratogenic risks. Requires monitoring for diarrhea, rash, and hepatotoxicity. Store in a cool, dry place under inert atmosphere to maintain stability.