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Overview
N-Boc-1-aminocyclobutanecarboxylic acid is a protected amino acid building block widely used in organic synthesis. Its molecular formula is C9H15NO4 and CAS number is 207889-86-3.
Application
- Peptide Chemistry: Serves as a non-natural residue for constructing cyclic peptides and constrained analogs to enhance metabolic stability.
- Drug Discovery: Utilized as a scaffold in lead optimization for developing novel pharmaceutical agents targeting CNS disorders.
- Material Science: Applied in synthesizing specialized polymers with unique conformational properties.
Precautions
- Storage: Maintain at -20°C in a dry, inert atmosphere to prevent hydrolysis of the Boc group.
- Safety: Handle with appropriate PPE; avoid inhalation or skin contact as it may cause irritation.
- Regulatory: Intended strictly for research use; not approved for direct clinical administration without further formulation.