Category:
Other Specialized Reagents
Standard:
In-house Standards,
N4-tac-DMT-dC-CE-Phosphoramidite is a specialized phosphoramidite monomer designed for automated solid-phase oligonucleotide synthesis. Its structure incorporates a dimethoxytrityl (DMT) protecting group, a triazole-based linker (tac), and a cyanoethyl (CE) phosphite moiety attached to N4-acetyl-deoxycytidine. This reagent enables the efficient incorporation of modified cytosine residues into DNA strands.
Store under inert atmosphere at -20°C to prevent hydrolysis. Handle in a fume hood due to potential toxicity of phosphoramidites. Strictly exclude moisture during synthesis to maintain coupling efficiency.