Category:
Fine Chemicals
CAS NO:
1374774-70-5
Standard:
In-house Standards,
Naldemedine is a peripherally acting mu-opioid receptor antagonist (PAMORA) developed to treat opioid-induced constipation. The core synthesis involves complex chiral resolution and functional group manipulation. Its molecular formula is C29H40N2O7 with CAS number 1235658-59-9.
Strictly contraindicated in patients with known or suspected gastrointestinal obstruction. Storage requires controlled room temperature away from moisture to maintain chemical stability and potency during logistics handling.