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Overview
Nemadectin is a macrocyclic lactone derivative synthesized via fermentation, primarily used as a research tool in neuropharmacology. It acts as a potent agonist at glutamate-gated chloride channels (GluCls). Molecular Formula: C28H40O7. CAS Number: 159616-64-5.
Application
- Insecticide Development: Screening for novel pest control agents targeting nematodes and arthropods.
- Neuroscience Research: Investigating synaptic transmission mechanisms in invertebrate models.
- Agricultural Science: Evaluating efficacy against soil-borne plant parasitic nematodes.
Precautions
Strictly for laboratory use only; not approved for human or veterinary therapeutic applications. Store under inert atmosphere at -20°C to prevent degradation. Handle with appropriate PPE due to potential neurotoxicity in non-target organisms.