Category:
Active Pharmaceutical Ingredients
CAS NO:
641571-10-0
Standard:
In-house Standards,
Nilotinib is a second-generation tyrosine kinase inhibitor (TKI) synthesized via advanced organic catalysis. It targets BCR-ABL1 with high specificity to treat Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML). Molecular Formula: C25H27N7O; CAS No: 418960-46-8.
Strictly contraindicated for patients with prolonged QT interval or severe hepatic impairment. Requires storage in tightly sealed containers at controlled temperatures between 20°C and 25°C to maintain chemical stability and potency.