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Overview
Nintedanib is a potent, small-molecule tyrosine kinase inhibitor (TKI) primarily synthesized via multi-step organic coupling. Its molecular formula is C25H26N6O4 with CAS number 678049-13-1.
Application
- Treatment of idiopathic pulmonary fibrosis (IPF).
- Management of non-small cell lung cancer (NSCLC).
- Control of chronic fibrosing interstitial lung diseases.
Precautions
Contraindicated in patients with active liver disease or severe hepatic impairment. Store at controlled room temperature away from moisture. Monitor liver enzymes regularly during clinical administration.