Category:
Active Pharmaceutical Ingredients
CAS NO:
656247-18-6
Standard:
In-house Standards,
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Nintedanib Esylate is a potent, small-molecule tyrosine kinase inhibitor (TKI) used primarily for treating fibrotic disorders. Manufactured via chemical synthesis involving nintedanib base and esylic acid, its molecular formula is C28H30N4O7S with CAS No. 1269507-14-7.
Contraindicated in patients with severe hepatic impairment or hypersensitivity to the compound. Strict storage is required at controlled room temperature (20-25°C) in dry conditions to maintain stability. Clinical use mandates monitoring of liver enzymes and gastrointestinal adverse events.