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Overview
Niraparib tosylate is a PARP inhibitor salt used in oncology. Synthesized via reaction of niraparib free base with p-toluenesulfonic acid, its molecular formula is C26H31N4O5S and CAS number is 1070867-99-6.
Application
- Oncology manufacturing for ovarian cancer treatment protocols.
- Clinical trials supply for BRCA-mutated malignancies.
- Pharmaceutical formulation development for oral tablet production.
Precautions
Contraindicated in pregnancy; requires strict GMP storage below 25°C in dry conditions. Personnel must utilize appropriate PPE during handling to avoid inhalation or skin contact.