Nifurantoin, also known as furantantin, furantanidine, nifurantoin, nitrofurantoin. This product is bright yellow crystalline powder, odorless, bitter taste, deep gradient in light. It is dissolved in dimethyl formamide, in acetone, in ethanol, and almost insoluble in water or chloroform. Mainly used for urinary tract infection caused by sensitive bacteria.
Melting point: 268℃ [2]
Refraction rate: 1.52 (20c)
Flash point: 43
Density: 0.915 g/cm3 (20 C)
Water solubility: <0.01 g/100 mL at 19 ° C
Exterior view: lemon yellow crystalline powder
Organic synthesis and biochemical research. Medicine. This product is an excellent antibacterial drug with wide antibacterial spectrum. After oral administration, it can be absorbed quickly and completely and excreted quickly. The excretion amount in urine can reach 40-50%. It has effects on gram-negative and positive bacteria, mainly used for urinary tract infection caused by sensitive bacteria, especially for acute urinary tract infection caused by e. coli and proteus. Clinically used for urinary system infection caused by sensitive bacteria, such as pyelonephritis, urinary tract infection, cystitis and prostatitis
Nitrofurantoin (CAS: 67-20-9) is a broad-spectrum nitrofuran antibiotic synthesized via the condensation of 5-nitro-2-furaldehyde with hydantoin. Its molecular formula is C8H6N4O5.
Contraindicated in patients with significant renal impairment or pregnancy at term. Store in tightly closed containers below 25°C, protected from light and moisture to maintain stability.