Category:
Active Pharmaceutical Ingredients
CAS NO:
459789-99-2
Standard:
In-house Standards,
Obeticholic Acid is a synthetic bile acid derivative used as a FXR agonist. The chemical formula is C24H30O5 with CAS No. 128794-17-6. Core synthesis involves modification of cholic acid precursors via enzymatic or chemical pathways to enhance receptor affinity.
Contraindicated in patients with complete biliary obstruction or severe hepatic impairment. Storage requires cool, dry conditions below 25°C to maintain stability. Strict adherence to dosage guidelines is critical due to risks of hepatotoxicity and pruritus.